JAK3 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-31846-20uL | 20uL | £125.00 |
Quantity:
| E-AB-31846-60uL | 60uL | £172.00 |
Quantity:
| E-AB-31846-120uL | 120uL | £237.00 |
Quantity:
| E-AB-31846-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
JAK3
Background:
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Calculated MW:
125kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
Immunogen:
Synthesized peptide derived from human JAK3 around the non-phosphorylation site of Tyr785.
ObservedMW:
125kDa
Purification method:
Affinity purification
Target Synonym:
EC 2.7.10.2;JAK 3;JAK L;JAK-3;Jak3;JAK3 HUMAN;JAK3;JAKL;Janus kinase 3 (a protein tyrosine kinase;leukocyte);Janus kinase 3;Janus Kinase3;L JAK;L-JAK;Leukocyte janus kinase;LJAK;Protein tyrosine kinase leukocyte;Tyrosine protein kinase JAK3;Tyrosine-protein kinase JAK3
UNIProt ID:
P52333