ITGB3BP Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-10402-20uL | 20uL | £125.00 |
Quantity:
| E-AB-10402-60uL | 60uL | £172.00 |
Quantity:
| E-AB-10402-120uL | 120uL | £237.00 |
Quantity:
| E-AB-10402-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
ITGB3BP
Background:
This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.7 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human ITGB3BP
Purification method:
Affinity purification
Target Synonym:
Beta 3 endonexin;Beta3 endonexin;Beta3 endonexin long form;CENP R;CENPR;CENPR;Centromere protein R;endonexin;Beta-3;HSU37139;Integrin beta 3 binding protein (beta3-endonexin);Integrin beta 3 binding protein;NRIF 3;NRIF3;Nuclear receptor interacting factor 3;TAP 20;TAP20
UNIProt ID:
Q13352