IRF4 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-13342-20uL | 20uL | £125.00 |
Quantity:
| E-AB-13342-60uL | 60uL | £172.00 |
Quantity:
| E-AB-13342-120uL | 120uL | £237.00 |
Quantity:
| E-AB-13342-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
IRF4
Background:
The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
52kDa
Concentration:
0.2 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1:1000
Immunogen:
Synthetic peptide of human IRF4
Purification method:
Affinity purification
Target Synonym:
Interferon regulatory factor 4;IRF 4;IRF-4;Irf4;IRF4;LSIRF;Lymphocyte specific interferon regulatory factor;Lymphocyte specific IRF;Lymphocyte-specific interferon regulatory factor;Multiple myeloma oncogene 1;MUM 1;MUM1;NF EM5;NF-EM5;NFEM5;PU.1 interaction partner;Sfpi1/PU.1 interaction partner;Transcriptional activator PIP
UNIProt ID:
Q15306