IQGAP3 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-10405-20uL | 20uL | £125.00 |
Quantity:
| E-AB-10405-60uL | 60uL | £172.00 |
Quantity:
| E-AB-10405-120uL | 120uL | £237.00 |
Quantity:
| E-AB-10405-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
IQGAP3
Background:
IQGAP3 (IQ motif containing GTPase activating protein 3) is a 1,631 amino acid protein that acts as an effector of Cdc42 and Rac 1, linking their activation to the cytoskeleton during neuronal morphogenesis. A novel member of the IQGAP family, IQGAP3 is highly expressed in brain where it localizes to axons of hippocampal neurons. IQGAP3 contains one Ras-GAP domain, a CH (calponin-homology) domain, four IQ domains and is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson?s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
185kDa
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1:1000
Immunogen:
Recombinant protein of human IQGAP3
Purification method:
Affinity purification
Target Synonym:
IQ motif containing GTPase activating protein 3;IQGA3;IQGAP 3;IQGAP3;MGC10170;MGC10831;MGC1947;OTTHUMP00000031854;OTTHUMP00000031855;Ras GTPase activating like protein IQGAP3;Ras GTPase-activating-like protein IQGAP3
UNIProt ID:
Q86VI3