IPO4 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-15136-20uL | 20uL | £125.00 |
Quantity:
| E-AB-15136-60uL | 60uL | £172.00 |
Quantity:
| E-AB-15136-120uL | 120uL | £237.00 |
Quantity:
| E-AB-15136-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
IPO4
Background:
Importin-4is aproteinthat in humans is encoded by theIPO4gene. Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
119kDa
Concentration:
0.2 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:200
Immunogen:
Recombinant protein of human IPO4
Purification method:
Affinity purification
Target Synonym:
Imp4;Imp4b;Importin 4;Importin 4b;Importin-4;Importin-4b;Ipo4;IPO4;Ran binding protein 4;Ran-binding protein 4;RanBP4
UNIProt ID:
Q8TEX9