INHBB Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-17341-20uL | 20uL | £125.00 |
Quantity:
| E-AB-17341-60uL | 60uL | £172.00 |
Quantity:
| E-AB-17341-120uL | 120uL | £237.00 |
Quantity:
| E-AB-17341-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
INHBB
Background:
The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.8 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:30-150, ELISA 1:2000-10000
Immunogen:
Synthetic peptide of human INHBB
Purification method:
Affinity purification
Target Synonym:
Activin beta B chain;Activin beta-B chain;INHBB;INHBB;Inhibin beta 2;Inhibin beta B chain;Inhibin beta B subunit
UNIProt ID:
P09529