INHBA Polyclonal Antibody

INHBA

The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

47kDa

0.6 mg/mL

Unconjugated

WB 1:1000-1:2000

Synthetic peptide of human INHBA

Affinity purification

Activin beta-A chain;EDF;Erythroid differentiation factor;Erythroid differentiation protein;Follicle stimulating hormone releasing protein;FRP;FSH releasing protein;INHBA;INHBA;Inhibin beta A chain;Inhibin beta A subunit;Inhibin;beta 1;Inhibin;beta A (activin A;activin AB alpha polypeptide)

P08476