IMPDH2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-11330-20uL | 20uL | £125.00 |
Quantity:
| E-AB-11330-60uL | 60uL | £172.00 |
Quantity:
| E-AB-11330-120uL | 120uL | £237.00 |
Quantity:
| E-AB-11330-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
IMPDH2
Background:
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
56kDa
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:200
Immunogen:
Recombinant protein of human IMPDH2
Purification method:
Affinity purification
Target Synonym:
IMDH2;IMP (inosine monophosphate) dehydrogenase 2;IMP dehydrogenase 2;IMP oxireductase 2;IMPD 2;IMPD2;IMPDH 2;IMPDH II;IMPDH-II;Impdh2;Inosine 5' monophosphate dehydrogenase 2;Inosine 5' phosphate dehydrogenase 2;Inosine monophosphate dehydrogenase type II;Inosine-5''-monophosphate dehydrogenase 2
UNIProt ID:
P12268