IL5RA Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-16515-20uL | 20uL | £125.00 |
Quantity:
| E-AB-16515-60uL | 60uL | £172.00 |
Quantity:
| E-AB-16515-120uL | 120uL | £237.00 |
Quantity:
| E-AB-16515-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
IL5RA
Background:
The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
48kDa
Concentration:
0.9 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1:1000, IHC 1:50-1:200
Immunogen:
Synthetic peptide of human IL5RA
Purification method:
Affinity purification
Target Synonym:
CD125;CD125 antigen;CDw125;HSIL5R3;IL-5 receptor subunit alpha;IL-5R subunit alpha;IL-5R-alpha;IL-5RA;IL5R;IL5RA;IL5RA;Interleukin 5 Receptor alpha;Interleukin 5 Receptor alpha chain;Interleukin 5 receptor alpha subunit;Interleukin 5 receptor subunit alpha;Interleukin 5 receptor type 3;Interleukin-5 receptor subunit alpha;MGC26560
UNIProt ID:
Q01344