IL18BP Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-13876-20uL | 20uL | £125.00 |
Quantity:
| E-AB-13876-60uL | 60uL | £172.00 |
Quantity:
| E-AB-13876-120uL | 120uL | £237.00 |
Quantity:
| E-AB-13876-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
IL18BP
Background:
The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human IL18BP
Purification method:
Affinity purification
Target Synonym:
I18BP;IL-18BP;IL18 BP;IL18 BPa;IL18BP;IL18BPa;Interleukin 18 binding protein;Interleukin-18-binding protein;MC51L 53L 54L homolog gene product;Tadekinig alfa;Tadekinig-alfa
UNIProt ID:
O95998