IL12RB2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-13323-20uL | 20uL | £125.00 |
Quantity:
| E-AB-13323-60uL | 60uL | £172.00 |
Quantity:
| E-AB-13323-120uL | 120uL | £237.00 |
Quantity:
| E-AB-13323-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
IL12RB2
Background:
The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. Several transcript variants encoding different isoforms and non-protein coding transcripts have been found for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human IL12RB2
Purification method:
Affinity purification
Target Synonym:
I12R2;IL-12 receptor subunit beta-2;IL-12R subunit beta-2;IL-12R-beta-2;IL-12RB2;IL12 receptor beta 2;IL12R beta2;IL12RB2;Interleukin 12 receptor beta 2;Interleukin 12 receptor beta 2 chain;Interleukin-12 receptor subunit beta-2;RP11 102M16.1
UNIProt ID:
Q99665