IL10RA Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-10098-20uL | 20uL | £125.00 |
Quantity:
| E-AB-10098-60uL | 60uL | £172.00 |
Quantity:
| E-AB-10098-120uL | 120uL | £237.00 |
Quantity:
| E-AB-10098-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
IL10RA
Background:
The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:25-1:100
Immunogen:
Recombinant protein of human IL10RA
Purification method:
Affinity purification
Target Synonym:
CD210;CDw210a;CDw210a antigen;HIL 10R;HIL10R;I10R1;IL 10R 1;IL 10R A;IL 10R;IL 10R1;IL-10 receptor subunit alpha;IL-10R subunit 1;IL-10R subunit alpha;IL-10R1;IL-10RA;IL10R;IL10R1;IL10RA;Interleukin 10 receptor alpha;Interleukin 10 receptor alpha chain;Interleukin-10 receptor subunit 1;Interleukin-10 receptor subunit alpha
UNIProt ID:
Q13651