IKBIP Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-11324-20uL | 20uL | £125.00 |
Quantity:
| E-AB-11324-60uL | 60uL | £172.00 |
Quantity:
| E-AB-11324-120uL | 120uL | £237.00 |
Quantity:
| E-AB-11324-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
IKBIP
Background:
IKIP (Inhibitor of nuclear factor kappa-B kinase-interacting protein, IKK-interacting protein) is a single-pass membrane protein that shares a common promoter with APAF1. APAF1 and IKIP are both induced by X irradiation, however, the two gene products are transcribed in different directions. The IKIP gene is believed to be a target for p53 as expression of IKIP has been shown to promote apoptosis. IKIP has four known isoforms, three of which are found traversing the endoplasmic reticulum membrane. IKIP isoform 4 has a deletion of the transmembrane region which leads to a homogenous distribution of the protein within the cell. The IKIP gene products are expressed in vascular endothelial cells, while the isoform 4 has also been detected in lung, kidney, spleen, thymus and skeletal muscle.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human IKBIP
Purification method:
Affinity purification
Target Synonym:
FLJ31051;I kappa B kinase interacting protein;IKBIP;IKBKB interacting protein;IKIP1;IKIP2;IKIP3;IKK interacting protein;Inhibitor of nuclear factor kappa B kinase interacting protein
UNIProt ID:
Q70UQ0