IDH2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-11319-20uL | 20uL | £125.00 |
Quantity:
| E-AB-11319-60uL | 60uL | £172.00 |
Quantity:
| E-AB-11319-120uL | 120uL | £237.00 |
Quantity:
| E-AB-11319-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
IDH2
Background:
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
51kDa
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300
Immunogen:
Recombinant protein of human IDH2
Purification method:
Affinity purification
Target Synonym:
D2HGA2;ICD-M;IDH;IDH2;IDHM;IDHP;IDP;IDPM;Isocitrate dehydrogenase [NADP];mitochondrial;Isocitrate dehydrogenase 2 (NADP+);mitochondrial;mNADP-IDH;NADP(+)-specific ICDH;Oxalosuccinate decarboxylase
UNIProt ID:
P48735