IDH1 Polyclonal Antibody

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Elabscience
Product Code: E-AB-30163
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-30163-20uL20uL£125.00
Quantity:
E-AB-30163-60uL60uL£172.00
Quantity:
E-AB-30163-120uL120uL£237.00
Quantity:
E-AB-30163-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C

Images

1 / 2
Western Blot analysis of 293T, Hela cells with IDH1 Polyclonal Antibody.
2 / 2
Immunohistochemistry of paraffin-embedded Human kidney tissue using IDH1 Polyclonal Antibody at dilution of 1:100.
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Western Blot analysis of 293T, Hela cells with IDH1 Polyclonal Antibody.
Immunohistochemistry of paraffin-embedded Human kidney tissue using IDH1 Polyclonal Antibody at dilution of 1:100.

Documents

Further Information

Abbreviation:
IDH1
Background:
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Calculated MW:
47kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000-1:20000
Immunogen:
Synthesized peptide derived from the N-terminal region of human IDH1.
ObservedMW:
46kDa
Purification method:
Affinity purification
Target Synonym:
Cytosolic NADP isocitrate dehydrogenase;Cytosolic NADP-isocitrate dehydrogenase;Epididymis luminal protein 216;Epididymis secretory protein Li 26;HEL-216;HEL-S-26;ICDH;IDCD;IDH;IDH1;IDHC;IDP;IDPC;Isocitrate dehydrogenase (NADP(+)) 1 cytosolic;Isocitrate dehydrogenase [NADP] cytoplasmic;Isocitrate dehydrogenase 1 (NADP+) soluble;NADP dependent isocitrate dehydrogenase cytosolic;NADP dependent isocitrate dehydrogenase peroxisomal;NADP(+)-specific ICDH;Oxalosuccinate decarboxylase;PICD
UNIProt ID:
O75874