IAPP Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-12243-20uL | 20uL | £125.00 |
Quantity:
| E-AB-12243-60uL | 60uL | £172.00 |
Quantity:
| E-AB-12243-120uL | 120uL | £237.00 |
Quantity:
| E-AB-12243-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
IAPP
Background:
Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the association of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.8 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human IAPP
Purification method:
Affinity purification
Target Synonym:
Amylin;DAP;Diabetes associated peptide;Diabetes-associated peptide;IAP;IAPP;IAPP;Insulinoma amyloid peptide;Islet amyloid polypeptide (diabetes associated peptide;amylin);Islet amyloid polypeptide
UNIProt ID:
P10997