HYAL3 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-11316-20uL | 20uL | £125.00 |
Quantity:
| E-AB-11316-60uL | 60uL | £172.00 |
Quantity:
| E-AB-11316-120uL | 120uL | £237.00 |
Quantity:
| E-AB-11316-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
HYAL3
Background:
This gene encodes a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. The regulated turnover of hyaluronan plays a critical role in many biological processes including cell proliferation, migration and differentiation. The encoded protein may also play an important role in sperm function. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression, and the expression of specific transcript variants may be indicative of tumor status. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and some isoforms may lack hyaluronidase activity. This gene overlaps and is on the same strand as N-acetyltransferase 6 (GCN5-related), and some transcripts of each gene share a portion of the first exon.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
47kDa
Concentration:
0.2 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:200
Immunogen:
Recombinant protein of human HYAL3
Purification method:
Affinity purification
Target Synonym:
Hyal-3;HYAL3;HYAL3;Hyaluronidase 3;Hyaluronidase-3;Hyaluronoglucosaminidase 3;Hyaluronoglucosaminidase-3;LUCA-3;LUCA14;LUCA3;Lung carcinoma protein 3;Minna14
UNIProt ID:
O43820