HYAL2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-15116-20uL | 20uL | £125.00 |
Quantity:
| E-AB-15116-60uL | 60uL | £172.00 |
Quantity:
| E-AB-15116-120uL | 120uL | £237.00 |
Quantity:
| E-AB-15116-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
HYAL2
Background:
This gene encodes a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments of hyaluronan are thought to be involved in cell proliferation, migration and differentiation. Although it was previously thought to be a lysosomal hyaluronidase that is active at a pH below 4, the encoded protein is likely a GPI-anchored cell surface protein. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5' UTR.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human HYAL2
Purification method:
Affinity purification
Target Synonym:
Hyal 2;Hyal-2;Hyal2;HYAL2;Hyaluronidase 2;Hyaluronidase 2 Precursor;Hyaluronidase-2;Hyaluronoglucosaminidase 2;Hyaluronoglucosaminidase-2;LUCA 2;LUCA-2;LUCA2;Lung carcinoma protein 2;lysosomal hyaluronidase;PH 20 homolog;PH-20 homolog;PH20 homolog
UNIProt ID:
Q12891