HTRA3 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-13006-20uL | 20uL | £125.00 |
Quantity:
| E-AB-13006-60uL | 60uL | £172.00 |
Quantity:
| E-AB-13006-120uL | 120uL | £237.00 |
Quantity:
| E-AB-13006-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
HTRA3
Background:
HtrA3, also known as PRSP (pregnancy-related serine protease), is a 453 amino acid secreted protein that contains one PDZ domain, one Kazal-like domain and one IGFBP N-terminal domain. Widely expressed with particularly high expression in ovary, heart, placenta and bladder, HtrA3 functions as a probable serine protease that is thought to play an important role in placental development. HtrA3 is downregulated in ovarian tumors, suggesting an alternative role in tumor suppression. HtrA3 exists as two alternatively spliced isoforms, designated short and long. The gene encoding HtrA3 maps to human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.2 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human HTRA3
Purification method:
Affinity purification
Target Synonym:
High temperature requirement factor A3;High-temperature requirement factor A3;HtrA serine peptidase 3;HTRA3;HTRA3;Pregnancy related serine protease;Pregnancy-related serine protease;Probable serine protease HTRA3;PRSP;Serine protease HTRA3;Tasp
UNIProt ID:
P83110