HSD3B7 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-11311-20uL | 20uL | £125.00 |
Quantity:
| E-AB-11311-60uL | 60uL | £172.00 |
Quantity:
| E-AB-11311-120uL | 120uL | £237.00 |
Quantity:
| E-AB-11311-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
HSD3B7
Background:
This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human HSD3B7
Purification method:
Affinity purification
Target Synonym:
3 beta HSD VII;3 beta hydroxy Delta(5) C27 steroid oxidoreductase;3 beta hydroxysteroid dehydrogenase type 7;3 beta hydroxysteroid dehydrogenase type VII;AI195443;BB098564;C(27) 3 beta HSD;Cca2;Cholest 5 ene 3 beta;7 alpha diol 3 beta dehydrogenase;Confluent 3Y1 cell associated 2;Hydroxy delta 5 steroid dehydrogenase;3 beta and steroid delta isomerase 7;OTTMUSP00000018894;OTTMUSP00000018895;OTTMUSP00000018897;PFIC4;SDR11E3
UNIProt ID:
Q9H2F3