HSD17B2 Polyclonal Antibody

Elabscience
Product Code: E-AB-11304
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-11304-20uL20uL£125.00
Quantity:
E-AB-11304-60uL60uL£172.00
Quantity:
E-AB-11304-120uL120uL£237.00
Quantity:
E-AB-11304-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C

Images

1 / 3
Western Blot analysis of Human fetal liver tissue using HSD17B2 Polyclonal Antibody at dilution of 1:300
2 / 3
Immunohistochemistry of paraffin-embedded Human esophagus cancer using HSD17B2 Polyclonal Antibody at dilution of 1:50
3 / 3
Immunohistochemistry of paraffin-embedded Human brain  using HSD17B2 Polyclonal Antibody at dilution of 1:50

Western Blot analysis of Human fetal liver tissue using HSD17B2 Polyclonal Antibody at dilution of 1:300
Immunohistochemistry of paraffin-embedded Human esophagus cancer using HSD17B2 Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human brain  using HSD17B2 Polyclonal Antibody at dilution of 1:50

Documents

Further Information

Abbreviation:
HSD17B2
Background:
17β-HSD2 (17β hydroxysteroid dehydrogenase type 2) belongs to the 17β-HSD family of proteins that regulate the availability of steroids within a tissue. 17β-HSD2 converts active steroids to their inactive form through its oxidative activity. It is a key player in the inactivation of Estradiol and testosterone. Due to the affects that 17β-HSD2 has on the availability of estrogen, it has been extensively investigated for playing a possible role in breast tumor development, colon cancer development and the pathophysiology of endometriosis.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
43kDa
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:200
Immunogen:
Recombinant protein of human HSD17B2
Purification method:
Affinity purification
Target Synonym:
17 beta HSD 2;17-beta-HSD 2;17-beta-hydroxysteroid dehydrogenase type 2;20 alpha HSD;20 alpha hydroxysteroid dehydrogenase;20 alpha-hydroxysteroid dehydrogenase;20-alpha-HSD;DHB2;E2DH;EDH17B2;Estradiol 17-beta-dehydrogenase 2;HSD17;Hsd17b2;Hydroxysteroid (17 beta) dehydrogenase 2;Microsomal 17 beta hydroxysteroid dehydrogenase;Microsomal 17-beta-hydroxysteroid dehydrogenase;SDR9C2;Short chain dehydrogenase/reductase family 9C;member 2;Testosterone 17 beta dehydrogenase;Testosterone 17-beta-dehydrogenase
UNIProt ID:
P37059