HSD17B12 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-11302-20uL | 20uL | £125.00 |
Quantity:
| E-AB-11302-60uL | 60uL | £172.00 |
Quantity:
| E-AB-11302-120uL | 120uL | £237.00 |
Quantity:
| E-AB-11302-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
HSD17B12
Background:
This gene encodes a very important 17beta-hydroxysteroid dehydrogenase (17beta-HSD) that converts estrone into estradiol in ovarian tissue. This enzyme is also involved in fatty acid elongation. Catalyzes the transformation of estrone (E1) into estradiol (E2), suggesting a central role in estrogen formation. Its strong expression in ovary and mammary gland suggest that it may constitute the major enzyme responsible for the conversion of E1 to E2 in women.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
34kDa
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1:1000, IHC 1:50-1:200
Immunogen:
Recombinant protein of human HSD17B12
Purification method:
Affinity purification
Target Synonym:
12;3-ketoacyl-CoA reductase;short chain;17 beta HSD 12;17 beta hydroxysteroid dehydrogenase 12;17-@beta-HSD XII;17-@beta-hydroxysteroid dehydrogenase XII;17-beta-HSD 12;17-beta-hydroxysteroid dehydrogenase 12;17beta HSD type 12;3 ketoacyl CoA reductase;3-ketoacyl-CoA reductase;DHB12;Estradiol 17 beta dehydrogenase 12;Estradiol 17-beta-dehydrogenase 12;HSD17B12;Hydroxysteroid (17-beta) dehydrogenase 12;KAR;KIK-I;Kik1;SDR12C1;Short chain dehydrogenase/reductase family 12C member 1;Steroid dehydrogenase homolog
UNIProt ID:
Q53GQ0