HNF1B Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-12661-20uL | 20uL | £125.00 |
Quantity:
| E-AB-12661-60uL | 60uL | £172.00 |
Quantity:
| E-AB-12661-120uL | 120uL | £237.00 |
Quantity:
| E-AB-12661-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
HNF1B
Background:
This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.9 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:100-1:300
Immunogen:
Synthetic peptide of human HNF1B
Purification method:
Affinity purification
Target Synonym:
FJHN;Hepatocyte nuclear factor 1 beta;Hepatocyte nuclear factor 1-beta;HNF 1B;HNF 2;HNF-1-beta;HNF-1B;HNF1 beta;HNF1 homeobox B;HNF1B;HNF1B;HNF1beta;HNF2;Homeoprotein LF B3;Homeoprotein LFB3;HPC11;LF B3;LFB3;MODY 5;MODY5;TCF 2;TCF 2 protein;TCF-2;TCF2;TCF2 protein;Transcription factor 2;Transcription factor 2 hepatic;Variant hepatic nuclear factor 1;Variant hepatic nuclear factor;VHNF 1;vHNF1
UNIProt ID:
P35680
References
- https://www.ncbi.nlm.nih.gov/pmc/articles/pmc8273515/