HK2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-14706-20uL | 20uL | £125.00 |
Quantity:
| E-AB-14706-60uL | 60uL | £172.00 |
Quantity:
| E-AB-14706-120uL | 120uL | £237.00 |
Quantity:
| E-AB-14706-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
HK2
Background:
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
102kDa
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:5000, IHC 1:100-1:300
Immunogen:
Recombinant protein of human HK2
Purification method:
Affinity purification
Target Synonym:
DKFZp686M1669;Hexokinase 2;Hexokinase 2 muscle;Hexokinase type II;Hexokinase-2;HK 2;HK II;HK2;HKII;HxK 2;HxK2;HXK2;Muscle form hexokinase
UNIProt ID:
P52789
References
- https://link.springer.com/article/10.1186/s12929-022-00855-6
- https://www.frontiersin.org/articles/10.3389/fonc.2021.618705/full
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279700/