Histone H2B Monoclonal Antibody
| Code | Size | Price |
|---|
| E-AB-22086-20uL | 20uL | £125.00 |
Quantity:
| E-AB-22086-60uL | 60uL | £172.00 |
Quantity:
| E-AB-22086-120uL | 120uL | £237.00 |
Quantity:
| E-AB-22086-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: Clone:3C3
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
Histone H2B
Background:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. HIST1H2BB (Histone Cluster 1 H2B Family Member B) is a Protein Coding gene. Among its related pathways are DNA Double-Strand Break Repair and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. GO annotations related to this gene include sequence-specific DNA binding and protein heterodimerization activity. An important paralog of this gene is HIST1H2BN.
Buffer:
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Calculated MW:
14kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-3000, IF 1:100-200
Immunogen:
Synthetic Peptide
ObservedMW:
14kDa
Purification method:
Protein A purification
Target Synonym:
HIST1H2BA;testis;bA317E16.3;H2B;H2B histone family member U;H2B histone family member U testis specific;H2B histone family;member U;(testis specific);H2B testis;H2B1A;H2BFU;H2BT;HIST1H2BA;Histone 1;H2ba;Histone cluster 1 H2ba;Histone H2B;Histone H2B testis;Histone H2B type 1 A;Histone H2B type 1-A;Histone H2B type 1A;STBP;Testis specific histone H2B;Testis-specific histone H2B;TSH 2B;TSH2B;TSH2B.1
UNIProt ID:
P33778