HGF Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-14122-20uL | 20uL | £125.00 |
Quantity:
| E-AB-14122-60uL | 60uL | £172.00 |
Quantity:
| E-AB-14122-120uL | 120uL | £237.00 |
Quantity:
| E-AB-14122-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
HGF
Background:
Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.8 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human HGF
Purification method:
Affinity purification
Target Synonym:
DFNB39;F TCF;Fibroblast derived tumor cytotoxic factor;Hepatocyte growth factor (hepapoietin A;scatter factor);Hepatocyte growth factor;Hepatocyte growth factor beta chain;Hepatocyte growth factor precursor;Hepatopoietin A;Hepatopoietin-A;Hgf;HGF;HGFB;HPTA;Lung fibroblast derived mitogen;OTTHUMP00000161349;OTTHUMP00000206710;OTTHUMP00000206711;OTTHUMP00000206712;OTTHUMP00000206713;OTTHUMP00000206730;Scatter factor;SF
UNIProt ID:
P14210