HDAC2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-31644-20uL | 20uL | £125.00 |
Quantity:
| E-AB-31644-60uL | 60uL | £172.00 |
Quantity:
| E-AB-31644-120uL | 120uL | £237.00 |
Quantity:
| E-AB-31644-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Monkey
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
HDAC2
Background:
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.Forms transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR. Interacts in the late S-phase of DNA-replication with DNMT1 in the other transcriptional repressor complex composed of DNMT1, DMAP1, PCNA, CAF1. Deacetylates TSHZ3 and regulates its transcriptional repressor activity.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Calculated MW:
55kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
Immunogen:
Synthesized peptide derived from human HDAC2 around the non-phosphorylation site of Ser394.
ObservedMW:
55kDa
Purification method:
Affinity purification
Target Synonym:
D10Wsu179e;HD 2;HD2;HDAC 2;Hdac2;HDAC2;Histone deacetylase 2 (HD2);Histone deacetylase 2;OTTHUMP00000017046;OTTHUMP00000227077;OTTHUMP00000227078;RPD3;transcriptional regulator homolog RPD3;YAF1;YY1 associated factor 1;YY1 transcription factor binding protein;Yy1bp
UNIProt ID:
Q92769