HACE1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-16474-20uL | 20uL | £125.00 |
Quantity:
| E-AB-16474-60uL | 60uL | £172.00 |
Quantity:
| E-AB-16474-120uL | 120uL | £237.00 |
Quantity:
| E-AB-16474-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
HACE1
Background:
HACE1 (HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1), also known as KIAA1320, is a 909 amino acid protein that localizes to both the cytoplasm and the endoplasmic reticulum and contains one HECT domain and six ANK repeats. Expressed in kidney, heart and brain, HACE1 functions as an E3 ubiquitin-protein ligase that interacts with the proteasome and is thought to play a role in protein degradation. HACE1 is downregulated in Wilms tumor, suggesting a possible role in tumor suppression.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
1.5 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:100-1:200
Immunogen:
Synthetic peptide of human HACE1
Purification method:
Affinity purification
Target Synonym:
E3 ubiquitin-protein ligase HACE1;HACE 1;HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1;KIAA1320
UNIProt ID:
Q8IYU2