GRPR Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-12444-20uL | 20uL | £125.00 |
Quantity:
| E-AB-12444-60uL | 60uL | £172.00 |
Quantity:
| E-AB-12444-120uL | 120uL | £237.00 |
Quantity:
| E-AB-12444-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
GRPR
Background:
Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
43kDa
Concentration:
1.1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1:1000, IHC 1:50-1:200
Immunogen:
Synthetic peptide of human GRPR
Purification method:
Affinity purification
Target Synonym:
BB2;Bombesin BB2 receptor;bombesin receptor 2;Gastrin Releasing Peptide Receptor;Gastrin-releasing peptide receptor;GRP preferring bombesin receptor;GRP R;GRP-preferring bombesin receptor;GRP-R;Grp/bombesin receptor;Grpr;GRPR
UNIProt ID:
P30550