GPR124 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-13277-20uL | 20uL | £125.00 |
Quantity:
| E-AB-13277-60uL | 60uL | £172.00 |
Quantity:
| E-AB-13277-120uL | 120uL | £237.00 |
Quantity:
| E-AB-13277-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
GPR124
Background:
Tumor endothelial markers (TEMs) are abundantly expressed in the blood vessels of human solid tumors during angiogenesis and neoangiogensis. These include TEM1 (endosialin), TEM5 (G-protein coupled receptor 124) and TEM7 (plexin domain containing 1). TEMs are associated with the cell surface membrane at low levels in normal human and mouse tissues. TEM5 is a seven-pass transmembrane receptor, whereas TEM1, TEM7 and TEM8 span the membrane once. TEM5 expression is elevated during tumor angiogenesis and neoangiogenesis. TEM7 is highly expressed in tumor endothelium and neurons. Therefore, TEM5 and TEM7 may be suitable targets for the development of antiangiogenic therapies.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human GPR124
Purification method:
Affinity purification
Target Synonym:
DKFZp434C211;DKFZp434J0911;FLJ14390;G protein coupled receptor 124;G-protein coupled receptor 124;GP124;GPR 124;Gpr124;KIAA1531;TEM 5;TEM5;Tumor endothelial marker 5;Tumor endothelial marker 5 precursor
UNIProt ID:
Q96PE1