CD42b Polyclonal Antibody

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Elabscience
Product Code: E-AB-11281
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-11281-20uL20uL£125.00
Quantity:
E-AB-11281-60uL60uL£172.00
Quantity:
E-AB-11281-120uL120uL£237.00
Quantity:
E-AB-11281-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C

Images

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Western Blot analysis of Mouse liver tissue using CD42b Polyclonal Antibody at dilution of 1:800
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Immunohistochemistry of paraffin-embedded Human liver cancer using CD42b Polyclonal Antibody at dilution of 1:60
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Immunohistochemistry of paraffin-embedded Spleen tissue using CD42b Polyclonal Antibody at dilution of 1:80(Elabscience Product Detected by Lifespan).
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Western Blot analysis of Mouse liver tissue using CD42b Polyclonal Antibody at dilution of 1:800
Immunohistochemistry of paraffin-embedded Human liver cancer using CD42b Polyclonal Antibody at dilution of 1:60
Immunohistochemistry of paraffin-embedded Spleen tissue using CD42b Polyclonal Antibody at dilution of 1:80(Elabscience Product Detected by Lifespan).

Documents

Further Information

Abbreviation:
GP1BA
Background:
Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease. The coding region of this gene is known to contain a polymophic variable number tandem repeat (VNTR) domain that is associated with susceptibility to nonarteritic anterior ischemic optic neuropathy.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
72kDa
Concentration:
0.8 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300
Immunogen:
Recombinant protein of human GP1BA
Purification method:
Affinity purification
Target Synonym:
Antigen CD42b alpha;BDPLT1;BDPLT3;BSS;CD 42b;CD42b alpha;CD42B;CD42b antigen;DBPLT3;GLYCOCALICIN;Glycoprotein Ib (platelet) alpha polypeptide;Glycoprotein Ibalpha;GP Ib alpha;GP1B;GP1BA;GPIb alpha;GPIbA;MGC34595;Platelet glycoprotein Ib alpha chain;Platelet glycoprotein Ib alpha polypeptide;Platelet membrane glycoprotein 1b alpha subunit;VWDP
UNIProt ID:
P07359