GADD45B Polyclonal Antibody

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Elabscience
Product Code: E-AB-15054
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-15054-20uL20uL£125.00
Quantity:
E-AB-15054-60uL60uL£172.00
Quantity:
E-AB-15054-120uL120uL£237.00
Quantity:
E-AB-15054-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C

Images

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Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using GADD45B Polyclonal Antibody at dilution 1:40
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Immunohistochemistry of paraffin-embedded Human brain tissue using GADD45B Polyclonal Antibody at dilution 1:40
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Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using GADD45B Polyclonal Antibody at dilution 1:40
Immunohistochemistry of paraffin-embedded Human brain tissue using GADD45B Polyclonal Antibody at dilution 1:40

Documents

Further Information

Abbreviation:
GADD45B
Background:
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human GADD45B
Purification method:
Affinity purification
Target Synonym:
GA45B;GADD45 Beta;Gadd45b;GADD45BETA;Growth arrest and DNA damage inducible 45 beta;Growth arrest and DNA damage inducible beta;Growth arrest and DNA damage-inducible gene GADD45;beta;Growth arrest and DNA damage-inducible protein GADD45 beta;Growth arrest and DNA-damage-inducible protein GADD45 beta;MY118;MYD118;MYD118;mouse;homolog of;Myeloid differentiation primary response gene;Myeloid differentiation primary response protein MyD118;Negative growth regulatory protein MyD118;Negative growth-regulatory protein MyD118
UNIProt ID:
O75293