GAD2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-15661-20uL | 20uL | £125.00 |
Quantity:
| E-AB-15661-60uL | 60uL | £172.00 |
Quantity:
| E-AB-15661-120uL | 120uL | £237.00 |
Quantity:
| E-AB-15661-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
GAD2
Background:
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:25-1:100
Immunogen:
Synthetic peptide of human GAD2
Purification method:
Affinity purification
Target Synonym:
65 kDa glutamic acid decarboxylase;DCE 2;DCE2;DCE2;GAD 2;GAD 65;GAD-2;GAD-65;Gad2;Glutamate decarboxylase 2 (pancreas);Glutamate Decarboxylase 2 (pancreatic islets and brain 65kDa);Glutamate decarboxylase 2;Glutamate Decarboxylase 65;Glutamate decarboxylase 65 kDa isoform;Glutamic Acid Decarboxylase 2;Glutamic Acid Decarboxylase 65;MGC161605;MGC161607
UNIProt ID:
Q05329