GAD1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-17390-20uL | 20uL | £125.00 |
Quantity:
| E-AB-17390-60uL | 60uL | £172.00 |
Quantity:
| E-AB-17390-120uL | 120uL | £237.00 |
Quantity:
| E-AB-17390-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
GAD1
Background:
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
67 kDa
Concentration:
0.2 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1000, IHC 1:25-100, ELISA 1:1000-2000
Immunogen:
Synthetic peptide of human GAD1
Purification method:
Affinity purification
Target Synonym:
67 kDa glutamic acid decarboxylase;CPSQ1;DCE1;DCE1;EC 4.1.1.15;FLJ45882;GAD 67;GAD;GAD-67;GAD1;Glutamate decarboxylase 1 (brain;67kDa);Glutamate decarboxylase 1;Glutamate decarboxylase 1 brain 67kD;Glutamate decarboxylase 1 brain 67kDa;Glutamate decarboxylase 67 kDa isoform;Glutamate decarboxylase;brain;67-KD;OTTHUMP00000041055;SCP
UNIProt ID:
Q99259