GAB2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-15052-20uL | 20uL | £125.00 |
Quantity:
| E-AB-15052-60uL | 60uL | £172.00 |
Quantity:
| E-AB-15052-120uL | 120uL | £237.00 |
Quantity:
| E-AB-15052-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
GAB2
Background:
This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
74kDa
Concentration:
0.2 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:200
Immunogen:
Recombinant protein of human GAB2
Purification method:
Affinity purification
Target Synonym:
GAB 2;Gab2;GAB2;Grb 2 associated binder 2;GRB 2 associated binding protein 2;Grb2 associated binder 2;GRB2 associated binder 2 pp100;GRB2 associated binding protein 2;GRB2-associated binder 2;GRB2-associated-binding protein 2;Growth factor receptor bound protein 2 associated protein 2;Growth factor receptor bound protein 2-associated protein 2;KIAA0571;p97;PH domain containing adaptor molecule p97;pp100
UNIProt ID:
Q9UQC2