FTO Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-15049-20uL | 20uL | £125.00 |
Quantity:
| E-AB-15049-60uL | 60uL | £172.00 |
Quantity:
| E-AB-15049-120uL | 120uL | £237.00 |
Quantity:
| E-AB-15049-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
FTO
Background:
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
58kDa
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300
Immunogen:
Recombinant protein of human FTO
Purification method:
Affinity purification
Target Synonym:
AlkB homolog 9;ALKBH9;Alpha-ketoglutarate-dependent dioxygenase FTO;AW743446;Fat mass and obesity-associated protein;FATSO;MOUSE;HOMOLOG OF;Fto;FTO;GDFD;KIAA1752;mKIAA1752;Protein fatso
UNIProt ID:
Q9C0B1