FOXL2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-15650-20uL | 20uL | £125.00 |
Quantity:
| E-AB-15650-60uL | 60uL | £172.00 |
Quantity:
| E-AB-15650-120uL | 120uL | £237.00 |
Quantity:
| E-AB-15650-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
FOXL2
Background:
This gene encodes a forkhead transcription factor. The protein contains a fork-head DNA-binding domain and may play a role in ovarian development and function. Mutations in this gene are a cause of blepharophimosis syndrome and premature ovarian failure 3. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
50kDa
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Synthetic peptide of human FOXL2
Purification method:
Affinity purification
Target Synonym:
Blepharophimosis;Blepharophimosis epicanthus inversus and ptosis 1;Blepharophimosis epicanthus inversus and ptosis;BPES 1;BPES;BPES1;Epicanthus inversus and ptosis 1;Forkhead box L2;Forkhead box protein L2;Forkhead transcription factor FOXL2;FOX L2;FOXL 2;FOXL2;FOXL2;PFRK;PINTO;PITUITARY FORKHEAD FACTOR;POF 3;POF3
UNIProt ID:
P58012