FLNA Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-15040-20uL | 20uL | £125.00 |
Quantity:
| E-AB-15040-60uL | 60uL | £172.00 |
Quantity:
| E-AB-15040-120uL | 120uL | £237.00 |
Quantity:
| E-AB-15040-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
FLNA
Background:
The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
281kDa
Concentration:
0.8 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:5000, IHC 1:50-1:200
Immunogen:
Recombinant protein of human FLNA
Purification method:
Affinity purification
Target Synonym:
ABP 280;ABP-280;Actin-binding protein 280;Alpha filamin;Alpha-filamin;APBX;CSBS;CVD1;Endothelial actin binding protein;Endothelial actin-binding protein;Filamin 1;Filamin A alpha;Filamin A;Filamin-1;Filamin-A;FLN;FLN-A;FLN1;FLNA;FLNA;FMD;MNS;NHBP;Non muscle filamin;Non-muscle filamin;OPD;OPD1;OPD2;XLVD;XMVD
UNIProt ID:
P21333