FH Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-15051-20uL | 20uL | £125.00 |
Quantity:
| E-AB-15051-60uL | 60uL | £172.00 |
Quantity:
| E-AB-15051-120uL | 120uL | £237.00 |
Quantity:
| E-AB-15051-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
FH
Background:
The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
55kDa
Concentration:
0.7 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:200
Immunogen:
Recombinant protein of human FH
Purification method:
Affinity purification
Target Synonym:
FH;Fumarase;Fumarate hydratase;Fumarate hydratase mitochondrial;Fumarate hydratase;mitochondrial;FUMH;HLRCC;LRCC;MCL;MCUL 1;MCUL1;MS709;Multiple hereditary cutaneous leiomyomata
UNIProt ID:
P07954