FGFR1OP Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-11232-20uL | 20uL | £125.00 |
Quantity:
| E-AB-11232-60uL | 60uL | £172.00 |
Quantity:
| E-AB-11232-120uL | 120uL | £237.00 |
Quantity:
| E-AB-11232-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
FGFR1OP
Background:
This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.7 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:100-1:300
Immunogen:
Recombinant protein of human FGFR1OP
Purification method:
Affinity purification
Target Synonym:
FOP
UNIProt ID:
O95684