FBXW7 Polyclonal Antibody

Elabscience
Product Code: E-AB-14856
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-14856-20uL20uL£125.00
Quantity:
E-AB-14856-60uL60uL£172.00
Quantity:
E-AB-14856-120uL120uL£237.00
Quantity:
E-AB-14856-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C

Images

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Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using FBXW7 Polyclonal Antibody at dilution 1:30
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Immunohistochemistry of paraffin-embedded Human liver cancer tissue using FBXW7 Polyclonal Antibody at dilution 1:30

Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using FBXW7 Polyclonal Antibody at dilution 1:30
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using FBXW7 Polyclonal Antibody at dilution 1:30

Documents

Further Information

Abbreviation:
FBXW7
Background:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene was previously referred to as FBX30, and belongs to the Fbws class; in addition to an F-box, this protein contains 7 tandem WD40 repeats.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human FBXW7
Purification method:
Affinity purification
Target Synonym:
AGO;Archipelago;Archipelago homolog;Archipelago;Drosophila;homolog of;CDC4;CDC4;S.cerevisiae;homolog of;DKFZp686F23254;F box and WD 40 domain protein 7 (archipelago homolog;Drosophila);F box and WD 40 domain protein 7;F box and WD repeat domain containing 7;F box protein FBW7;F box protein FBX30;F box protein SEL 10;F box protein SEL10;F-box and WD repeat domain containing 7;E3 ubiquitin protein ligase;F-box and WD-40 domain-containing protein 7;F-box protein FBX30;F-box/WD repeat-containing protein 7;FBW6;FBW7;FBX30;FBXO30;FBXW6;FBXW7;FBXW7;FLJ16457;hAgo;hCdc4;Homolog of C elegans sel 10;Homolog of C.elegans sel10;SEL 10;SEL-10;SEL10
UNIProt ID:
Q969H0