Fibulin 5 Polyclonal Antibody
Code | Size | Price |
---|
E-AB-12408-20uL | 20uL | £125.00 |
Quantity:
E-AB-12408-60uL | 60uL | £172.00 |
Quantity:
E-AB-12408-120uL | 120uL | £237.00 |
Quantity:
E-AB-12408-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Images
Further Information
Abbreviation:
FBLN5
Background:
The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3).
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
1.2 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human FBLN5
Purification method:
Affinity purification
Target Synonym:
ADCL2;ARCL1A;ARMD3;Dance;Developmental arteries and neural crest EGF like protein;Developmental arteries and neural crest EGF-like protein;EVEC;Fbln5;FBLN5;FIBL 5;FIBL-5;Fibulin-5;FLJ90059;UP50;Urine p50 protein
UNIProt ID:
Q9UBX5