FAT1 Polyclonal Antibody
Code | Size | Price |
---|
E-AB-13237-20uL | 20uL | £125.00 |
Quantity:
E-AB-13237-60uL | 60uL | £172.00 |
Quantity:
E-AB-13237-120uL | 120uL | £237.00 |
Quantity:
E-AB-13237-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Images
Further Information
Abbreviation:
FAT1
Background:
This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human FAT1
Purification method:
Affinity purification
Target Synonym:
Cadherin family member 7;Cadherin family member 7 precursor;Cadherin ME5;Cadherin related tumor suppressor;Cadherin related tumor suppressor homolog;Cadherin related tumor suppressor homolog precursor;Cadherin related tumor suppressor homolog precursor (FAT protein homolog);Cadherin-related tumor suppressor homolog;CDHF 7;CDHF7;FAT 1;FAT tumor suppressor 1;FAT tumor suppressor homolog 1;FAT1;FAT1;hFat 1;hFAT;hFat1;Homolog of Drosophila FAT protein;Homolog of Drosophila FAT protein precursor;Homolog of Drosophila tumor suppressor FAT precursor;ME 5;ME5;nuclear form;Protein fat homolog;Protocadherin Fat 1
UNIProt ID:
Q14517
References
- https://www.mdpi.com/1948780