FAM3B Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-15013-20uL | 20uL | £125.00 |
Quantity:
| E-AB-15013-60uL | 60uL | £172.00 |
Quantity:
| E-AB-15013-120uL | 120uL | £237.00 |
Quantity:
| E-AB-15013-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
FAM3B
Background:
FAM3B (family with sequence similarity 3, member B), also known as ORF9, C21orf11 or PANDER, is a 235 amino acid secreted protein that localizes to discrete vesicular and perinuclear structures. Expressed at high levels in pancreas and at lower levels in kidney, colon, testis, prostate and small intestine, FAM3B functions as an islet-specific cytokine that promotes apoptosis and may inhibit Insulin secretion from beta-cells, possibly playing a role in overall pancreatic activity. Human FAM3B shares 78% sequence identity with its mouse counterpart, suggesting a conserved role between species. Three isoforms of FAM3B, designated A, B and C, exist due to alternative splicing events. The gene encoding FAM3B maps to human chromosome 21, which houses approximately 300 genes and comprises nearly 1.5% of the human genome.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human FAM3B
Purification method:
Affinity purification
Target Synonym:
2-21;C21orf11;C21orf76;Cytokine like protein 2 21;Cytokine-like protein 2-21;Fam3b;FAM3B;Family with sequence similarity 3 member B;ORF9;Pancreatic-derived factor;PANDER;PRED44;Protein FAM3B
UNIProt ID:
P58499