F7 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-14394-20uL | 20uL | £125.00 |
Quantity:
| E-AB-14394-60uL | 60uL | £172.00 |
Quantity:
| E-AB-14394-120uL | 120uL | £237.00 |
Quantity:
| E-AB-14394-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
F7
Background:
This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
49kDa
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:25-1:100
Immunogen:
Recombinant protein of human F7
Purification method:
Affinity purification
Target Synonym:
coagulation factor VII (serum prothrombin conversion accelerator);Coagulation factor VII;Eptacog alfa;F7;FA7;Factor VII;Factor VII heavy chain;Factor VII light chain;FVII coagulation protein;OTTHUMP00000018733;OTTHUMP00000018734;Proconvertin;Serum prothrombin conversion accelerator;SPCA
UNIProt ID:
P08709