ESPL1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-13224-20uL | 20uL | £125.00 |
Quantity:
| E-AB-13224-60uL | 60uL | £172.00 |
Quantity:
| E-AB-13224-120uL | 120uL | £237.00 |
Quantity:
| E-AB-13224-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
ESPL1
Background:
Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 or STAG2 in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 by ESPL1, or separase, which initiates the final separation of sister chromatids.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
233kDa
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1:1000, IHC 1:25-1:100
Immunogen:
Synthetic peptide of human ESPL1
Purification method:
Affinity purification
Target Synonym:
Caspase like protein ESPL1;Caspase-like protein ESPL1;ESP 1;ESP1;ESPL 1;Espl1;ESPL1;Extra spindle poles like 1;Extra spindle poles like 1 protein;Extra spindle poles-like 1 protein;FLJ46492;KIAA0165;Separase;Separin;Similar to fission yeast cut1and gene;SSE
UNIProt ID:
Q14674