EPOR Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-15623-20uL | 20uL | £125.00 |
Quantity:
| E-AB-15623-60uL | 60uL | £172.00 |
Quantity:
| E-AB-15623-120uL | 120uL | £237.00 |
Quantity:
| E-AB-15623-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
EPOR
Background:
This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.7 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human EPOR
Purification method:
Affinity purification
Target Synonym:
EPO R;EPO-R;epor;EPOR;Erythropoietin receptor;Erythropoietin receptor precursor;MGC138358
UNIProt ID:
P19235