EIF4G1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-16401-20uL | 20uL | £125.00 |
Quantity:
| E-AB-16401-60uL | 60uL | £172.00 |
Quantity:
| E-AB-16401-120uL | 120uL | £237.00 |
Quantity:
| E-AB-16401-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
EIF4G1
Background:
The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
175kDa
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:25-1:100
Immunogen:
Synthetic peptide of human EIF4G1
Purification method:
Affinity purification
Target Synonym:
DKFZp686A1451;eIF 4 gamma 1;eIF 4G 1;eIF 4G1;eIF-4-gamma 1;eIF-4G 1;eIF-4G1;EIF4 gamma;EIF4F;EIF4G;EIF4G1;EIF4GI;Eukaryotic translation initiation factor 4 gamma 1;IF4G1;p220
UNIProt ID:
Q04637