EID1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-14978-20uL | 20uL | £125.00 |
Quantity:
| E-AB-14978-60uL | 60uL | £172.00 |
Quantity:
| E-AB-14978-120uL | 120uL | £237.00 |
Quantity:
| E-AB-14978-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
EID1
Background:
E1A-like inhibitor of differentiation-1 (EID-1), an acetyltransferase enzyme, binds both the retinoblastoma protein (Rb), a regulator of cell cycle and tissue specific transcription, and the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. EID-1 inhibits cellular differentiation by blocking the histone acetyltransferase activity of p300. EID-1 also acetylates both histones and non-histone proteins such as NCOA3 co-activator. By acetylating histones, EID-1 gives a specific tag for transcriptional activation. In addition to binding Rb and p300, EID-1 also binds to phosphorylated CREB protein, mediating cAMP gene regulation. EID-1 augments the activity of phosphorylated CREB and activates transcription of cAMP responsive genes as a co-activator.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human EID1
Purification method:
Affinity purification
Target Synonym:
21 kDa pRb associated protein;21 kDa pRb-associated protein;C15orf3;CBP;Chromosome 15 open reading frame 3;CREBBP/EP300 inhibitor 1;CREBBP/EP300 inhibitory protein 1;CRI 1;CRI1;E1A like inhibitor of differentiation;E1A-like inhibitor of differentiation 1;EID 1;EID-1;EID1;EID1;EP300 interacting inhibitor of differentiation 1;EP300-interacting inhibitor of differentiation 1;IRO45620;MGC138883;MGC138884;NB4 apoptosis related protein;PNAS 22;PNAS22;PTD014;Rb and p300 binding protein EID 1;Rb and p300 binding protein EID1;RBP21;Retinoblastoma protein associated protein
UNIProt ID:
Q9Y6B2