DYNLL1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-14954-20uL | 20uL | £125.00 |
Quantity:
| E-AB-14954-60uL | 60uL | £172.00 |
Quantity:
| E-AB-14954-120uL | 120uL | £237.00 |
Quantity:
| E-AB-14954-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
DYNLL1
Background:
Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human DYNLL1
Purification method:
Affinity purification
Target Synonym:
8 kDa dynein light chain;8kDLC;Cytoplasmic dynein light polypeptide;DLC1;DLC8;DNCL1;DNCLC1;DYL1;Dynein;cytoplasmic;light chain 1;Dynein light chain 1 cytoplasmic;Dynein light chain 1;cytoplasmic;Dynein light chain LC8 type 1;Dynein light chain LC8-type 1;Dynein;cytoplasmic;light polypeptide 1;Dynein;light chain;LC8-type 1;DYNLL1;HDLC1;LC8;LC8a;MGC126137;MGC126138;MGC72986;PIN;Protein inhibitor of neuronal nitric oxide synthase;Protein inhibitor of neuronal NOS
UNIProt ID:
P63167